All updates
All updates
today 17bioRxiv Cancer Biology精选评分5454 Nature Biotechnology评分33 Author Correction: Bioinstructive implantable scaffolds for rapid in vivo manufacture and release of CAR-T cells
bioRxiv Cancer Biology评分5252 Palmitate-activated IRE1-XBP1 signaling limits DNA damage and is associated with H2A.X-linked DNA damage response transcripts in triple-negative breast cancer cells
Nature Biotechnology精选评分4242 Accelerated discovery of thermostable mRNA–lipid nanoparticle vaccines using data-efficient AI
Nature Genetics精选评分5959 Germline homologous recombination deficiency influences TP53 -mutant clonal hematopoiesis fitness during platinum and PARP inhibitor treatment
Molecular Cell评分5151 ATM safeguards DNA replication by restraining pathological repriming at endogenous base lesions
Nature Biotechnology评分00 Lipid nanoparticles optimized for large RNA cargo and tissue targeting enhance in vivo genome editing
Nature Reviews Drug Discovery评分4040 Drug conjugate allows cell surface payload release
Nature Medicine评分3232 Biography of an inherited lung cancer risk gene
bioRxiv Cancer Biology精选评分6262 BLTP3A dysfunction unleashes lysosomal stress-induced antitumor immunity through STING
bioRxiv Cancer Biology精选评分6969 Pathway-wide base editing charts chemical-genetic interactions in MAPK signaling
监管与产业动态评分3939 Clinical outcomes and blood-based biomarkers across two SABR-treated metastatic settings: oligoprogression under immune checkpoint inhibition and oligometastatic disease
bioRxiv Cancer Biology精选评分6161 A druggable chromatin vulnerability in suppressive neutrophils restores antitumor immunity
Nature Biotechnology评分4545 Cargo size matters when designing lipid nanoparticles for delivery of large gene editors
bioRxiv Cancer Biology精选评分5858 Deciphering the association of spatial landscapes of DCIS with recurrence as invasive breast cancer
bioRxiv Cancer Biology评分5151 A plasma metabolomics workflow for breast cancer detection using quantitative GC/MS and machine learning
bioRxiv Cancer Biology评分4747 Spatial analysis of canine glioma reveals heterogeneous intratumoral niches characterized by distinct patterns of cell plasticity and immunosuppression
bioRxiv Cancer Biology精选评分6060 Systemic tumor-cell reprogramming converts solid tumors into in situ biofactories for immunotherapy
bioRxiv Cancer Biology精选评分6161 Glutamine and GLS1 are key metabolic checkpoints that Limit T cell Infiltration and Function in HNSCC
监管与产业动态评分3333 Integrated computational and experimental identification of a novel ML-IAP-targeting peptide with antiproliferative activity in leukaemia cells
Nature评分4949 Old hearts age backwards: transplanted organs adjust to host’s biological age
文献与产业新闻评分1818 Knowledge and attitudes of medical students about human papillomavirus (HPV) and HPV vaccine: A cross-sectional survey in Inner Mongolia, China
监管与产业动态评分1616 Knowledge and attitudes of medical students about human papillomavirus (HPV) and HPV vaccine: A cross-sectional survey in Inner Mongolia, China
bioRxiv Genomics精选评分4242 Integrative Nanopore and Illumina sequencing reveals age-associated tRNA modification and CCA-tail dynamics in yeast
bioRxiv Genomics精选评分5454 Targeted CRISPRi screening reveals unexpected resilience across the RNA polymerase III transcriptome
bioRxiv Genomics精选评分6262 A single-nucleus multi-omic atlas of gene regulation across 21 adult human tissues
文献与产业新闻精选评分4242 Assessing the consistency of overall survival extrapolations in Swedish health technology assessment reports of oncology treatments using extended follow-up data
文献与产业新闻精选评分5050 Plasma indole-3-propionic acid is a gut-derived metabolite and is associated with type 2 diabetes and cardiometabolic outcomes: Evidence from a human antibiotic intervention
监管与产业动态精选评分4040 Assessing the consistency of overall survival extrapolations in Swedish health technology assessment reports of oncology treatments using extended follow-up data
监管与产业动态精选评分5454 Plasma indole-3-propionic acid is a gut-derived metabolite and is associated with type 2 diabetes and cardiometabolic outcomes: Evidence from a human antibiotic intervention
中文产业新闻精选Chinese source评分6060 Cell研究提出铜死亡执行蛋白新机制，为耐药胃癌和肝癌提供干预思路
文献与产业新闻精选评分5959 Aurora kinase a phosphorylates and stabilizes UHRF1 to maintain DNA methylation and prostate cancer cell survival
文献与产业新闻评分2020 Coverage and appropriateness of influenza vaccination in adults ≥ 60 y: Provider contribution and adherence to Italian national recommendations
文献与产业新闻精选评分4040 Structure-based rational design and biological evaluation of a quinazoline-based EGFR exon 20 insertion inhibitor
文献与产业新闻评分2525 Real-world safety data of human papillomavirus vaccines after marketing in Shandong, China, August 2017-October 2025
文献与产业新闻精选评分3333 Circadian timing of first-line chemoimmunotherapy is associated with survival in extensive-stage small cell lung cancer
The Lancet Oncology评分3535 [Articles] Global uptake of essential cancer medicines with and without complex genomic diagnostics: a retrospective observational study
Nature Genetics精选评分5656 Single-cell analysis of chromatin accessibility in the human intestine identifies regulatory programs and clarifies genetic associations in Crohn’s disease
Nature Cancer精选评分5353 Stroke drives glioma progression through the emergence of tumor-associated astrocytes with reduced Ca 2+ activity
medRxiv Oncology评分4242 MRI-informed active surveillance outcomes and dietary fibre acceptability: the Aberdeen experience