All updates
All updates
today 15bioRxiv Genomics评分3737 bioRxiv Cancer Biology评分3838 Targeting REV7 exposes a mitotic vulnerability in colorectal cancer cells
中文产业新闻Chinese source评分6060 王洪/申龙/牛明明团队揭示FLT3信号适应性重塑驱动吉瑞替尼耐药新机制
中文产业新闻精选Chinese source评分6262 Cell：IRF1接管IRF2转录控制驱动先天免疫细胞激活的机制
中文产业新闻Chinese source评分5757 Cell | RNA结合蛋白TgPRO介导弓形虫代谢与氧化还原适应
中文产业新闻精选Chinese source评分6262 Cell：自体骨髓间充质干细胞外岩藻糖基化编辑用于骨质疏松治疗
文献与产业新闻评分3636 Real-life durability and virological outcomes of doravirine in people with multidrug-resistant HIV
监管与产业动态评分3636 Real-life durability and virological outcomes of doravirine in people with multidrug-resistant HIV
文献与产业新闻评分3636 Structure-guided discovery of novel ERα-binding peptides with in vitro antiproliferative activity
Science Translational Medicine评分2020 A single-dose topical therapy cures scabies in a human-relevant porcine model
Science Translational Medicine评分3939 Cranial bone marrow–derived monocytes promote neuroinflammation in chronic traumatic brain injury
Science Translational Medicine评分4444 Hyperosmotic niche adaptation and tissue polyamines underlie MRSA persistence in the kidney
Science Translational Medicine评分3838 Prime editing of human hematopoietic stem cells for correction of GATA2 deficiency
Science Translational Medicine评分3333 FAK inhibitor and RAF/MEK clamp avutometinib enhance KRAS G12C inhibitor efficacy in preclinical models of non–small cell lung cancer
Science Translational Medicine评分2222 Assessment of upper-limb motor recovery after stroke using a wrist-worn accelerometer digital biomarker
监管与产业动态评分3333 Chewing tobacco linked to 251,000 deaths worldwide, with more than 90% of health loss concentrated in 10 countries
监管与产业动态评分5656 Combination therapy emerges as possible treatment for an aggressive form of kidney cancer
监管与产业动态评分3737 HIV patients with cancer must travel farther than others to access clinical trials
Nature精选评分6868 A two-hit mechanism triggers autoimmune hair loss
Nature精选评分6161 A TBK1/ULK1 signalling axis couples lysosomal stress to TFEB activation
Nature精选评分5454 Spatiotemporal clonal architecture of the newborn mouse forebrain
Nature评分5252 γδ T cell receptor dependencies define a unique immunosurveillance modality
Nature精选评分6161 GPCR antagonism via rewiring of receptor trafficking and degradation
Nature精选评分6464 Transcription pause and elongation regulators mediate somatic hypermutation
Nature精选评分6060 Prion-like transmission of human tau strains in the mouse brain
Nature精选评分6363 Human genetics implicates a BACH2–NRF2 axis in fetal haemoglobin activation
Nature评分4444 Population-scale immune multiome atlas reveals regulatory disease mechanisms
Nature精选评分5757 Osteoclasts intercept meningeal lymphatic paths for dural metastasis
Nature评分5151 An amygdala to anterior hypothalamic circuit gates stress sensitivity
Nature评分3939 Carbene transfer from thianthrenium ylides for cyclopropanation
Nature精选评分7474 Histone readers MLLT1 and MLLT3 concentrate AID to confer locus specificity
Nature精选评分6262 Type 2 immune history trains lung macrophages for viral disease tolerance
Nature精选评分6969 Sugar-rich foods exacerbate antibiotic-induced microbiome disruption
Nature评分5656 Restoring hearing in people with a rare form of deafness
监管与产业动态精选评分7272 Atlas of immune cells explains how genetic variants cause disease
监管与产业动态评分3838 Insurance barriers limit access to blood cancer drugs
监管与产业动态评分5858 Investigators identify a metabolic weak point in exhausted immune cells in head and neck cancer
监管与产业动态评分5050 A deadly fungus may not live to see the last of us
bioRxiv Cancer Biology精选评分7070 RNA splicing factor mutations drive myeloid neoplasm oncogenesis through protein complex poisoning
bioRxiv Cancer Biology评分5656 Endothelial AMBRA1 loss contributes to vascular dysregulation facilitating metastatic progression in early-stage melanoma