All updates
All updates
today 15Science评分2929 Science评分2828 Hypertension fuels osteoarthritis through neuroendocrine signaling
Science评分3232 Loss of the tumor suppressor p53 generates a signaling gradient that drives epithelial clonal expansion
Science评分2929 Mitochondrial carrier SLC25A34 links clock, diet, and temperature control of adipocyte lipid cycling
NEJM评分3535 Survodutide Once Weekly in Adults with Obesity and Type 2 Diabetes
NEJM评分1111 Thyroglossal Duct Cyst
NEJM评分1010 An Echo Unheard
NEJM评分1212 Bilateral Pacing Neuromuscular Prosthesis for Laryngeal Paralysis
Nature Genetics精选评分6161 Reactivation of the embryonic ζ-globin gene ameliorates severe forms of α-thalassemia
Nature Medicine精选评分5656 Five-year survival with neoadjuvant therapy in melanoma: updated pooled analysis from the International Neoadjuvant Melanoma Consortium (INMC)
Nature评分2929 The ‘missed disease’ that affects 190 million: endometriosis drug shows early promise
Nature评分3939 Retraction Note: Ribosomal frameshifting in the CCR5 mRNA is regulated by miRNAs and the NMD pathway
bioRxiv Cancer Biology评分5555 Sustained Ion Imbalances Enhance Ferroptosis
bioRxiv Cancer Biology精选评分6666 Transcriptional rewiring of NF-κB by HBZ and Fra-2 drives inflammatory chemoresistance in Tax-negative adult T-cell leukemia/lymphoma
bioRxiv Cancer Biology评分3737 Clonogenic survival and relative biological effectiveness of pancreatic ductal adenocarcinoma under pristine and spread-out Bragg peak irradiation with protons and carbon ions.
bioRxiv Cancer Biology精选评分6464 Early dynamics of a neutrophil interferon program drive immunotherapy resistance and limit durable anti-tumor immunity
中文产业新闻Chinese source评分3737 把人iPSC来源的脑类器官种进小鼠大脑，长出人源皮层——这项研究做了什么？
中文产业新闻Chinese source评分3131 NEJM研究：1.6万名18-70岁无已知心血管疾病者超半数存在沉默性动脉粥样硬化
中文产业新闻精选Chinese source评分5656 郭纯洁等在Nature揭示BACH2-NRF2调控轴激活胎儿血红蛋白HbF的新机制
文献与产业新闻评分3030 Association of a Han Chinese urticaria-derived polygenic risk score with chronic spontaneous urticaria susceptibility and advanced systemic treatment use
顶刊论文（社媒热度）评分4646 Histologic Features and Clinical Outcomes of Lean Metabolic Dysfunction-Associated Steatotic Liver Disease.
顶刊论文（社媒热度）精选评分5353 Oral small-molecule GLP-1 receptor agonist safiglipron in early type 2 diabetes: a randomized, double-blind, placebo-controlled trial.
顶刊论文（社媒热度）评分4646 Microbiome signatures linked to cancer and treatment adverse events in a real-world cohort.
顶刊论文（社媒热度）精选评分6262 The early RNA decay factor ZC3H18 directs first intron splicing.
顶刊论文（社媒热度）精选评分6363 Transcription factor clusters enhance gene expression in vivo without modulating bursting dynamics.
顶刊论文（社媒热度）精选评分6464 Spatial evolution of a cachexia-promoting microenvironment in pancreatic cancer.
顶刊论文（社媒热度）精选评分7171 Gut microbiota primes stroke severity via the AHR in intestinal dendritic cells.
bioRxiv Cancer Biology评分4141 The Smac mimetic drug Xevinapant sensitizes triple negative breast cancer to radiotherapy-induced cell death in a TNFα dependent manner
bioRxiv Genomics评分2727 Intelligence and the Big Five personality traits share a genetic and biological basis
bioRxiv Genomics评分2828 Factors underlying creativity show distinct genetic architecture and genetic correlations with psychiatric disorders
Science精选评分6363 Hypertension fuels osteoarthritis through neuroendocrine signaling
Science精选评分7171 Mitochondrial carrier SLC25A34 links clock, diet, and temperature control of adipocyte lipid cycling
Science精选评分6363 Loss of the tumor suppressor p53 generates a signaling gradient that drives epithelial clonal expansion
Science评分3030 Sex-specific mechanisms of chronic pain
Science精选评分6464 Phage proteases activate CBASS antiphage immunity
bioRxiv Genomics评分3838 Whole-genome characterization of Plasmodium falciparum population structure and drug resistance across Uganda and neighboring countries
bioRxiv Genomics评分4444 Phylodynamic analysis reveals asymmetric and accelerating global spread of dengue virus
medRxiv Oncology评分3939 Lymphatic Spread Patterns in HPV+ vs. HPV- Oropharyngeal Squamous Cell Carcinoma: A Multi-Center European Analysis
bioRxiv Cancer Biology评分5858 Tumor suppressor-like mutations mark a dosage-constrained dependency in leukemia
bioRxiv Cancer Biology评分5050 Cell-of-origin shapes tumor subtype in BRCA1-associated triple-negative breast cancer