All updates
All updates
today 67bioRxiv Genomics评分5959 bioRxiv Genomics评分5858 High-throughput identification of chromatin-opening transcription factors
Molecular Cell精选评分6565 Oligo(uridine) tailing and exonucleolytic decay drive 40S ribosome degradation in response to stress
Molecular Cell评分5959 40S ribosome remodeling triggers 18S rRNA U-tailing and DIS3L2-dependent decay
bioRxiv Cancer Biology评分4848 Targeting ribosome biogenesis sensitizes PARPi-resistant triple-negative breast cancer
bioRxiv Cancer Biology评分3636 An Immunocompetent Mouse Model of Degarelix Induced Chemical Castration to Investigate Acquired Resistance to Androgen Deprivation.
bioRxiv Cancer Biology评分5656 Loss of the Y chromosome is transcriptionally silent in clear cell renal cell carcinoma and across cancer entities
bioRxiv Cancer Biology精选评分6565 The Red Blood Cell Surface Defines a Distinct Tumor DNA Compartment for Liquid Biopsy
Nature Cancer评分2222 Author Correction: PAK4 inhibition improves PD-1 blockade immunotherapy
顶刊论文（社媒热度）精选评分7474 A gut microbial odd-chain fatty acid alleviates atherosclerosis in mice.
顶刊论文（社媒热度）精选评分7575 A split attractor design for rapidly writing a navigational goal.
顶刊论文（社媒热度）精选评分7070 Structural basis for regulating lipopolysaccharide transmembrane transport.
顶刊论文（社媒热度）评分6767 Spatial omics resolves adrenergic and mesenchymal cell states in neuroblastoma.
顶刊论文（社媒热度）精选评分7777 Immunoregulatory gene GIMAP6 suppresses lethal atherosclerotic vasculopathy and ischemic heart failure.
顶刊论文（社媒热度）评分6565 Mechanistic insights into chromatin modulation by the "orphan" remodeler ATRX.
顶刊论文（社媒热度）评分5757 Kupffer cells are key mediators of antigen-specific immune tolerance by peptide-coupled red blood cells.
顶刊论文（社媒热度）评分5454 Rod photoreceptors have a dual dependency on both aerobic glycolysis and OXPHOS and diverge metabolically from other retinal neurons.
bioRxiv Cancer Biology评分5353 MYC drives endothelial transformation and dedifferentiation in angiosarcoma
bioRxiv Cancer Biology评分4949 Multi-Omic and Spatial Profiling Defines Outcome-Associated Tumor States in Head and Neck Adenoid Cystic Carcinoma
bioRxiv Cancer Biology评分5353 Behavioral dysfunction but not wasting in cancer cachexia is driven by altered tryptophan metabolism
中文产业新闻Chinese source评分6868 Nature论文：肝细胞通过提供丝氨酸支持胰腺癌肝转移
中文产业新闻Chinese source评分5050 戴连攀/高福/鲁帅尧联合团队揭示融合环改造寨卡疫苗猴子保护与ADE风险消除机制
bioRxiv Genomics评分5151 Single-nucleus multi-omics reveals reversible molecular signatures in skeletal muscle of patients with heart failure with preserved ejection fraction
bioRxiv Cancer Biology评分5151 Pdk1-dependent metabolic heterogeneity promotes aggressive colorectal cancer through cell-intrinsic interferon signaling
bioRxiv Cancer Biology评分3939 Regional reproducibility of immune expression programs in glioblastoma and implications for single-biopsy assessment
bioRxiv Cancer Biology评分5252 Tumour-stroma signaling drives a reversible program with neural-like features in cancer-associated fibroblasts
Nature评分3636 Chimp and gorilla brains resist weight loss with age — unlike human brains
bioRxiv Cancer Biology评分4141 Mathematical Modelling of Stochastic Gene Expression Quantifies mRNA Heterogeneity in Cancer Cell Populations with Extrachromosomal DNA
bioRxiv Cancer Biology评分2929 PIK-75 suppresses an SREBP-centred sterol programme in PIK3CA-altered small-cell lung cancer cells, but attribution to p110α remains unresolved
bioRxiv Cancer Biology评分5050 Epstein-Barr virus co-opts ADAR1 to evade PKR activation of the integrated stress response in nasopharyngeal carcinoma
社区讨论（Reddit）评分5353 Google’s AMIE system’s first real world study
社区讨论（Reddit）评分5454 Squeezing a Shinbone Heals Brain Injuries in Mice
中文产业新闻Chinese source评分6060 NEJM最新研究：10例晚期失明患者接受光遗传学基因治疗，6例出现具有临床意义的光敏感度改善
中文产业新闻精选Chinese source评分7070 广医边英杰团队 Cell 研究：癌细胞抢夺维生素 B2 抑制抗肿瘤免疫，补充可增强免疫治疗疗效
Nature Medicine评分4545 AI-assisted scoping review of code sharing in clinical prediction model research
中文产业新闻Chinese source评分6666 Nature论文：丝氨酸限制饮食联合靶向肝细胞代谢抑制胰腺癌肝转移
中文产业新闻精选Chinese source评分8181 Science 论文用 DNA Typewriter 重建活体小鼠从受精卵到 E13.5 的细胞谱系树
中文产业新闻Chinese source评分3636 卞修武/王斌团队绘制胃癌发生演进表观调控图谱，提出"癌前病变表观预备"并揭示免疫治疗耐药新亚型
中文产业新闻Chinese source评分6060 马文泰/李明锟团队合作揭示病毒受体结合蛋白几何结构如何塑造抗原进化轨迹
监管与产业动态评分4646 Balancing individual risks and collective benefits: Effects of vaccine price, message framing, and value orientations on influenza vaccination in China