NEJM· Matthew J. Frigault Binod Dhakal Andrzej J. Jakubowiak Noopur Raje Kamalika Banerjee C. Jenny Mu Kevin C. Hart Sigal Shachar Lawrence P. Andrews Laurene S. Cheung Faith M. Griffin Alexandra R. Witter Michael Hyde Chester Pham Nikitha Gandra Tenzin Shakya Bhargavi Rajan Christa Cortesio Samuel T. Haile Heba Nowyhed Priyanka Nair-Gupta Priyam Mitra Rebecca J. Chan Ana Kostic Christopher R. Heery Jacalyn Rosenblatt and Michael R. Bishop·· 9 天前精选评分45
Anito-cel（一种d-结构域BCMA CAR-T细胞）治疗难治性或复发性骨髓瘤的1期研究
Phase 1 Study of Anito-cel, a d-Domain BCMA CAR T Cell for Refractory or Recurrent Myeloma
导读
Anito-cel（一种靶向BCMA的d-结构域CAR-T细胞）在治疗难治性或复发性多发性骨髓瘤的1期临床试验中显示出良好的安全性和初步疗效。该研究评估了递增剂量水平下Anito-cel的安全性、耐受性和抗肿瘤活性。研究结果支持该疗法在复发/难治性多发性骨髓瘤患者中的进一步临床开发。
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来源：NEJM · nejm.org