medRxiv Oncology· Abelman, D. D., Eagles, J., Pedersen, S., Scott, D. S., Danesh, A., Bruce, J. P., Prokopec, S. D., Wong, A., Wei, E. N., Shah, S., White, D., Sandhu, I., Song, K., Murugesan, A., Reiman, A., Trudel, S., Pugh, T. J. ·· 18 天前精选评分45
匹配的骨髓与外周血分析揭示多发性骨髓瘤中液体活检信号的区室与特征特异性
Matched marrow and blood profiling reveals compartment- and feature-specific liquid-biopsy signals in multiple myeloma
导读
对74名多发性骨髓瘤患者的372份样本分析表明，外周血浆循环肿瘤DNA（cfDNA）在检测骨髓定义的拷贝数异常和突变方面不劣于骨髓血浆cfDNA，其恢复率分别为77.4%对72.0%和69.2%对65.4%。
来源：medRxiv Oncology · medrxiv.org