Erika Hamilton, MD, FASCO· @ErikaHamilton9 · X·· 2 天前评分70
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#APEXBr01: Rolditamig deuderuxtecan - ECD2 and ECD4 HER-2 ADC, DAR ~ 6
1st line cytotoxic for HER-2 low either TNBC or HR+, all PDL-1 neg
PFS in all HER-2 low pts: improved from 5.5 to 16.4 (HR 0.29)
OS trend HR 0.44
Heme tox most common, ILD 2.2% (no deaths)
#ESMO26
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