Young Kwang Chae, MD, MPH, MBA· @youngkwangchae · X·· 2026-04-19评分60
正文 · 原文
Cachexia doesn’t just waste muscle — it kills ICI response.
@DrR_DUNNE
#AACR26
Same TME mediators (IL-6, PGE2, TNF-α) driving wasting are driving immunotherapy resistance. Cachexic patients: 2.3 mo PFS vs 12.0 mo across 4 studies .
PGE2 is elevated in cachexic patients.
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