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Mario Balsa· @MarioBalsaMD · X·· 2 天前评分70

pembrolizumab

正文 · 机器翻译

🚨#ESMO26 IOV-COM-202:将 TILs 前置!Lifileucel 联合 pembrolizumab 用于未接受过 ICI 治疗的晚期黑色素瘤。

💥 ORR 62.5% | CR 29.2%
▪️ mPFS 19.8个月 | mDOR NR | 13/15 例缓解 ≥12个月

现在 TILVANCE-301 必须推进该信号 👀

@OncoAlert @OncoReporte @myESMO @_SEOM @GrupoMelanoma

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会议摘要
1239O按 Proffered paper: Gynaecological cancers 对上

NRG-GY020: Phase III randomized trial of radiation +/- MK-3475 (pembrolizumab) for newly diagnosed early-stage high intermediate risk (HIR) mismatch repair deficient (dMMR) endometrioid endometrial cancer

https://esmocongress.esmo.org
2071O按 Proffered paper: Melanoma and other skin tumours 对上

STARBOARD phase 3: A randomized, double-blind study of first-line (1L) encorafenib (enco), binimetinib (bini), and pembrolizumab (pembro) vs placebo (pbo) and pembro for unresectable locally advanced or metastatic BRAF V600-mutant melanoma

https://esmocongress.esmo.org
2072O按 Proffered paper: Melanoma and other skin tumours 对上

Efficacy and safety of lifileucel and pembrolizumab in patients with immune check point inhibitor-naïve advanced melanoma: Final results from IOV-COM-202 study

https://esmocongress.esmo.org
2217RONCT04746300按 Rapid oral: Genitourinary tumours, prostate, penile and testis 对上

Updated results from the phase 1b/2 KEYNOTE-365 cohort I: Pembrolizumab (pembro) + carboplatin and etoposide chemotherapy (chemo) or chemo alone for neuroendocrine prostate cancer (NEPC)

https://esmocongress.esmo.org
2683P按 NSCLC, metastatic 对上

First-line (1L) olomorasib + pembrolizumab in KRAS G12C-mutant NSCLC: Updated results from LOXO-RAS-20001 and SUNRAY-01

https://esmocongress.esmo.org

来源:Mario Balsa · x.com

CBACBA Frontier Insights (CFI)美国华人生物医药科技协会(CBA)www.cba-usa.org