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UT MD Anderson· @UTMDAnderson · X·· 2026-04-20评分60

zanidatamab

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ADC 下一代 — 载荷创新

zanidatamab 新辅助 · 无化疗 pCR 30%,HER2 下调 56%

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We have made considerable progress with Her2 targeting, especially in the first line, our Dr. Jaffer Ajani shared at #AACR26. Zanidatamab/tislelizumab/chemo may be given to Her2 positive gastroesophageal adenocarcinoma patients, regardless of PDL-1 status. #EndCancer

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会议摘要
CT012按 药名 zanidatamab 对上
A phase 2 single-arm open-label trial evaluating zanidatamab in patients with early stage HER2 positive breast cancer: The NeoZanHER Study

Vicente Valero, Paula R. Pohlmann, Jason Mouabbi, Xuelin Huang, Wei Qiao, Heather R. Alonzo, Rashmi Krishna Murthy, Gaiane M. Rauch, Taiwo Adesoye, Cristina M. Checka, William F. Symmans, Dmitri Grachev, Flora Alajajyan, Adaeze Nwosu-Iheme, Amy Hassan, Miral Mahesh Patel, Sharon H. Giordano, Kelly Hunt, Debasish Tripathy, Funda Meric-Bernstam

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来源:UT MD Anderson · x.com

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