Science Translational Medicine· Irene Peris, Terrance J. Haanen, Alexander Day, Jiang Hu, Catherine Callahan, Gabrielle Hodges-Onishi, Kaitlin P. Zawacki, Brian Tran, Alexis Harold, Amanda Dowdican, Charles A. Nino, Wei Huang, Daniel Leonard, Matthew Hinderman, Kelsey Barrie, Brynne Raines, Jaya Sangodkar, Sophie Boock, Varsha Shankar, Miranda Giambi, Silvia Romero-Murillo, Leah Arbitman, Shirish Shenolikar, George Trainor, Frederic Cachoux, Obdulia Rabal, Olga Gherbovet, Laura Fourmois, David L. Brautigan, Analisa V. DiFeo, Derek J. Taylor, Caitlin M. O’Connor, Goutham Narla·· 1 天前评分59
分子胶 RPT04402 在高级别子宫癌中恢复 PP2A AαB56αC 三聚体形成
Restoration of PP2A AαB56αC trimer formation by RPT04402 molecular glue in high-grade uterine cancer
导读
Science Translational Medicine 报道，分子胶 RPT04402 在高级别子宫癌背景下能恢复 PP2A AαB56αC 三聚体的形成。原文 DOI：10.1126/scitranslmed.ady4852，2026 年 10 月发表。
来源：Science Translational Medicine · science.org