Angela Lamarca· @DrAngelaLamarca · X·· 1 天前评分70
正文 · 机器翻译
iKRAS #Daraxonrasib 在既往治疗的 #PDAC 中，于 @myESMO #ESMO26
‼️亚组分析（注意统计效能）
👉G12D、G12V 和 G12R 的 PFS 获益
👉所有亚组均显示 OS 获益，但因样本量小而具挑战性
👉ORR 不一
#ESMOAmbassadors
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会议摘要
LBA82按 Proffered paper 1: Gastrointestinal tumour, upper digestive 对上
Daraxonrasib, a RAS(ON) multi-selective inhibitor vs chemotherapy in previously treated metastatic pancreatic adenocarcinoma (mPDAC): Additional subgroup analyses from the ph3 RASolute 302 study
https://esmocongress.esmo.org帖内回复
- Angela Lamarca@DrAngelaLamarca
@myESMO PDAC #guidelines (update August 2026) state: “greatest strength of evidence (…) KRAS G12-mutated” - acknowledged discrepancies between authors https://annalsofoncology.org/action/showPdf… #ESMOAmbassadors #ESMO26
来源：Angela Lamarca · x.com