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Dr Sarah Sammons· @drsarahsam · X·· 1 天前评分70

TROP2

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TROPION-Breast02 brain mets analysis at #ESMO26 (Dent). 1L Dato-DXd vs chemo, mTNBC, n=61 with BMs:

CNS PFS 9.5 vs 2.6 mo, HR 0.27

icORR (measurable) 62.5% vs 37.5%

Untreated BMs: OS HR 0.35
Longest icDoR ~27 mo

Preferred Trop2 ADC for brain Mets! @RebeccaDSing
Exploratory, small n, real CNS signal. #bcsm

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会议摘要
2631RO按 Rapid oral 1: NSCLC, metastatic 对上

First-line BAT8008 (TROP2-ADC) plus BAT1308 (anti-PD-1) for advanced NSCLC: Results from a multicenter phase 2 study

https://esmocongress.esmo.org

来源:Dr Sarah Sammons · x.com

CBACBA Frontier Insights (CFI)美国华人生物医药科技协会(CBA)www.cba-usa.org