Dr Sarah Sammons· @drsarahsam · X·· 1 day agoScore70
Body · original
TROPION-Breast02 brain mets analysis at #ESMO26 (Dent). 1L Dato-DXd vs chemo, mTNBC, n=61 with BMs:
CNS PFS 9.5 vs 2.6 mo, HR 0.27
icORR (measurable) 62.5% vs 37.5%
Untreated BMs: OS HR 0.35
Longest icDoR ~27 mo
Preferred Trop2 ADC for brain Mets! @RebeccaDSing
Exploratory, small n, real CNS signal. #bcsm
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Conference abstracts
2631ROmatched by Rapid oral 1: NSCLC, metastatic
First-line BAT8008 (TROP2-ADC) plus BAT1308 (anti-PD-1) for advanced NSCLC: Results from a multicenter phase 2 study
https://esmocongress.esmo.orgSource: Dr Sarah Sammons · x.com