bioRxiv Cancer Biology· Denbeigh, J. M., Kneringer, A., Radstake, W. E., Parisi, A., Barna, S., Hartzell, S., Kerschbaum-Gruber, S., Dias, A. B., Fischer, P., Fuchs, H., Slade, D. M., Georg, D., Beltran, C. J. ·· 1 天前精选评分37
胰腺导管腺癌在质子与碳离子原始及展宽布拉格峰辐照下的克隆存活与相对生物有效性
Clonogenic survival and relative biological effectiveness of pancreatic ductal adenocarcinoma under pristine and spread-out Bragg peak irradiation with protons and carbon ions.
导读
研究在180.1 MeV质子和352.4 MeV/u碳离子辐照PANC-1和BxPC-3胰腺导管腺癌细胞，沿布拉格曲线四个位点评估克隆存活与RBE。RBE随剂量平均传能线密度（LETD）升高而增加：质子RBE10远端超1.1，碳离子RBE10在PANC-1由2.3升至5.2、BxPC-3由1.3升至3.7。
来源：bioRxiv Cancer Biology · biorxiv.org