跳到正文
Yago Garitaonaindía· @YGaritaonaindia · X·· 18 小时前评分45

#MELANOMA

正文 · 机器翻译

🔥 #ESMO26 新辅助 IO 后,在 III 期 #melanoma 中省略 TLND

🎙️ van Akkooi

许多中心已采用局部、非循证策略,在 PRADO 之外省略 TLND。

两项试验将给出答案:
➡️ OMIT(NL):nivo+ipi,ILN MPR → 省略 TLND
➡️ MSLT-3:随机比较仅 ILN 与 TLND,根据疗效调整,n≈1,574

@_SEOM @myESMO @oncodaily

#IO

63 浏览 · 2 赞 · 0 转发 · 0 回复

会议摘要
2071O按 Proffered paper: Melanoma and other skin tumours 对上

STARBOARD phase 3: A randomized, double-blind study of first-line (1L) encorafenib (enco), binimetinib (bini), and pembrolizumab (pembro) vs placebo (pbo) and pembro for unresectable locally advanced or metastatic BRAF V600-mutant melanoma

https://esmocongress.esmo.org
2072O按 Proffered paper: Melanoma and other skin tumours 对上

Efficacy and safety of lifileucel and pembrolizumab in patients with immune check point inhibitor-naïve advanced melanoma: Final results from IOV-COM-202 study

https://esmocongress.esmo.org
2079P按 Melanoma 对上

Transcriptomic and epigenomic profiling of TIL products identifies determinants of clinical benefit in advanced melanoma

https://esmocongress.esmo.org
LBA1按 Presidential Symposium I 对上

INTerpath-001: Phase 3 study of the mRNA-based individualized neoantigen therapy (INT) intismeran autogene (intismeran) plus pembrolizumab (pembro) vs pembro alone for adjuvant treatment of resected stage IIB-IV melanoma (MEL)

https://esmocongress.esmo.org

来源:Yago Garitaonaindía · x.com

CBACBA Frontier Insights (CFI)美国华人生物医药科技协会(CBA)www.cba-usa.org