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Arndt Vogel· @ArndtVogel · X·· 21 小时前评分70

BRAF

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TRIDENTE: A phase II study of rechallenge with ENCO, BINI, and CET in BRAF V600E-mutant mCRC
#ESMO26 #ESMOAmbassadors
👉mPFS: 2.8 mo
👉mOS: 9.6 mo
👉ORR: 19%
🧐Supports biomarker-driven re-challenging concepts for 🎯therapies in CRC
@myESMO @ASCO

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会议摘要
2071O按 Proffered paper: Melanoma and other skin tumours 对上

STARBOARD phase 3: A randomized, double-blind study of first-line (1L) encorafenib (enco), binimetinib (bini), and pembrolizumab (pembro) vs placebo (pbo) and pembro for unresectable locally advanced or metastatic BRAF V600-mutant melanoma

https://esmocongress.esmo.org
788RO按 Rapid oral: Gastrointestinal tumours, lower digestive 对上

Encorafenib plus cetuximab (EC) beyond progression in combination with FOLFIRI in BRAF V600E metastatic colorectal cancer (mCRC) patients (pts) progressing on EC: Results from the ECLYPse phase II trial

https://esmocongress.esmo.org
NCT06578559NCT06578559按 - **标题 / Title:** Phase II Study of ctDNA-guided Encorafenib Plus Cetuximab Retreatment in Patients BRAF V600E Mutated mCRC 对上

- **标题 / Title:** Phase II Study of ctDNA-guided Encorafenib Plus Cetuximab Retreatment in Patients BRAF V600E Mutated mCRC

https://esmocongress.esmo.org
NCT06640166NCT06640166按 - **标题 / Title:** Encorafenib + Cetuximab Beyond Progression in Combination With FOLFIRI in Patients With BRAF V600E Mutated Metastatic Colorectal Cancer Progressing on Encorafenib + Cetuximab. 对上

- **标题 / Title:** Encorafenib + Cetuximab Beyond Progression in Combination With FOLFIRI in Patients With BRAF V600E Mutated Metastatic Colorectal Cancer Progressing on Encorafenib + Cetuximab.

https://esmocongress.esmo.org

来源:Arndt Vogel · x.com

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