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Arndt Vogel· @ArndtVogel · X·· 19 小时前评分70

BRAF

正文 · 机器翻译

TRIDENTE:一项在 BRAF V600E 突变的 mCRC 中使用 ENCO、BINI 和 CET 进行再挑战的 II 期研究
#ESMO26 #ESMOAmbassadors
👉mPFS:2.8 个月
👉mOS:9.6 个月
👉ORR:19%
🧐支持在 CRC 中针对 🎯疗法采用生物标志物驱动的再挑战理念
@myESMO @ASCO

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会议摘要
2071O按 Proffered paper: Melanoma and other skin tumours 对上

STARBOARD phase 3: A randomized, double-blind study of first-line (1L) encorafenib (enco), binimetinib (bini), and pembrolizumab (pembro) vs placebo (pbo) and pembro for unresectable locally advanced or metastatic BRAF V600-mutant melanoma

https://esmocongress.esmo.org
788RO按 Rapid oral: Gastrointestinal tumours, lower digestive 对上

Encorafenib plus cetuximab (EC) beyond progression in combination with FOLFIRI in BRAF V600E metastatic colorectal cancer (mCRC) patients (pts) progressing on EC: Results from the ECLYPse phase II trial

https://esmocongress.esmo.org
NCT06578559NCT06578559按 - **标题 / Title:** Phase II Study of ctDNA-guided Encorafenib Plus Cetuximab Retreatment in Patients BRAF V600E Mutated mCRC 对上

- **标题 / Title:** Phase II Study of ctDNA-guided Encorafenib Plus Cetuximab Retreatment in Patients BRAF V600E Mutated mCRC

https://esmocongress.esmo.org
NCT06640166NCT06640166按 - **标题 / Title:** Encorafenib + Cetuximab Beyond Progression in Combination With FOLFIRI in Patients With BRAF V600E Mutated Metastatic Colorectal Cancer Progressing on Encorafenib + Cetuximab. 对上

- **标题 / Title:** Encorafenib + Cetuximab Beyond Progression in Combination With FOLFIRI in Patients With BRAF V600E Mutated Metastatic Colorectal Cancer Progressing on Encorafenib + Cetuximab.

https://esmocongress.esmo.org

来源:Arndt Vogel · x.com

CBACBA Frontier Insights (CFI)美国华人生物医药科技协会(CBA)www.cba-usa.org