Stop by the #AACR26 Antibody-Drug Conjugates and Linker Engineering poster session to see work by Samuel Lawn and colleagues on the FRα-t...

Clinical Cancer Research· @CCR_AACR · X·2026-04-21 00:07· 2026-04-21评分60

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Stop by the #AACR26 Antibody-Drug Conjugates and Linker Engineering poster session to see work by Samuel Lawn and colleagues on the FRα-targeting antibody drug conjugate ZW191 bearing a novel TOP1 inhibitor and catch the related simultaneous publication.
https://
brnw.ch/21x1Lr5

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会议摘要

CT306NCT06555744按代号 ZW191 对上

Phase 1 first-in-human multicenter open-label study of ZW191, a folate receptor α (FRα)-targeting antibody-drug conjugate (ADC), in patients with advanced solid tumors: Part 1 dose-escalation results

Patricia LoRusso, David Sommerhalder, Kosei Hasegawa, Kenichi Harano, David S. Tan, Noboru Yamamoto, David M. O’Malley, Kathleen N. Moore, Sarah E. Church, Lin Lu, Sabeen Mekan, Pranshul Chauha, Jung-Yun Lee

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来源：Clinical Cancer Research · x.com