Stop by the #AACR26 Antibody-Drug Conjugates and Linker Engineering poster session to see work by Samuel Lawn and colleagues on the FRα-t...

Clinical Cancer Research· @CCR_AACR · X·2026-04-21 00:07· 2026-04-21评分60

正文 · 机器翻译

前往 #AACR26 抗体-药物偶联物与连接子工程海报分会，了解 Samuel Lawn 及其同事关于靶向 FRα、搭载新型 TOP1 抑制剂的抗体药物偶联物 ZW191 的研究，并关注相关同步发表的论文。
https://
brnw.ch/21x1Lr5

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会议摘要

CT306NCT06555744按代号 ZW191 对上

Phase 1 first-in-human multicenter open-label study of ZW191, a folate receptor α (FRα)-targeting antibody-drug conjugate (ADC), in patients with advanced solid tumors: Part 1 dose-escalation results

Patricia LoRusso, David Sommerhalder, Kosei Hasegawa, Kenichi Harano, David S. Tan, Noboru Yamamoto, David M. O’Malley, Kathleen N. Moore, Sarah E. Church, Lin Lu, Sabeen Mekan, Pranshul Chauha, Jung-Yun Lee

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来源：Clinical Cancer Research · x.com