Older adults at #ESMO26: MOIO (LBA10) on 3-monthly checkpoint inhibitors, TOP-1 (545RO) on omitting RT in older women with ER+ breast cancer, B-42 (LBA24) on extended letrozole, EV-302 in older patients (4761P). De-escalation is the theme this year. #GeriatricOncology #gerionc @myESMO @SIOGorg @siognah @SIOGnursing_AH @YoungSIOG @AlumniSiog @royalmarsdenNHS @ICR_London @royalmarsden