Science Translational Medicine· Anna Z. Wec, Alice Cho, Simone Pecetta, Xiaozhen Hu, Michael F. Bender, Adrian R. Laciak, Jacob Hou, Fanchong Jian, Elif N. Korkmaz, Arvind Sharma, Nathen Bopp, Steve Sazinsky, Daniela Montes-Berrueta, Tessa Speidel, Diana Lee, Pradeep Babu Jagadeesh Reddy, Yunlong Cao, Andrea Carfi, William R. Schief, Laura M. Walker·· 16 小时前评分62
Fc正交工程支持mRNA编码双抗的多重递送并约束病毒逃逸
Orthogonal Fc engineering enables multiplexed delivery of mRNA-encoded bispecific antibodies that constrain viral escape
导读
该研究通过Fc正交工程改造，使mRNA编码的双抗可被多重递送，并展示其约束病毒逃逸的能力。论文发表于Science Translational Medicine，DOI: 10.1126/scitranslmed.aeh1292。
来源：Science Translational Medicine · science.org