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AACR Annual Meeting 2026

April 17–22, 2026 · San Diego · 2418 items

← Medicinal chemistry beyond KRAS: CDK2, WEE1, SERD

zedoresertib

Clinical trial

3 people · 3 posts · 1 abstract

Records
Drug / trialReadoutSetting
zedoresertibzedoresertibA WEE1-path molecule on the floorEarly clinical
Other cases in this chapter
Evidence
First data disclosure of the Phase I trial of the first in class combination of WEE1 inhibitor zedoresertib with PKMYT1 inhibitor lunresertib in patients with advanced solid tumors harboring CCNE1, FBXW7, or PPP2R1A genomic alterations

Timothy A. Yap, Rahul Aggarwal, Elisa Fontana, Martin Hojgaard, Benedito A. Carneiro, Linda Duska, Patricia LoRusso, Siddhartha Yadav, Stephanie Lheureux, Cara Mathews, Ryan H. Moy, Nehal Lakhani, Mia Weiss, Joan Tymon-Rosario, Gerardo Colon-Otero, Ignacio Garrido-Laguna, Elisabeth K. Lee, Esteban Rodrigo Imedio, Jonathan Wessen, Luke Piggott, Vito Dozio, Noemie Luong, Christophe Mas, Alison M. Schram

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Floor
Apr 21Tue
Apr 20Mon
CBACBA Frontier Insights (CFI)Chinese Biopharmaceutical Association (CBA)www.cba-usa.org