MRG007 (CDH17 ADC) #ESMO26

Nice to see PK...

...but the exposure comment is ridiculous.

Calculated in ng/mL based on Cmax, but MW are very different (150000 vs 435)!

In reality exatecan exposure is high (6% of ADC AUC), especially for DAR4 ADC!

Here replotted (in nM/mL) 👇