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Nicholas Hornstein· @GIMedOnc · X·· 3 天前评分90

nivolumab

正文 · 机器翻译

临近 #ESMO26,热点成果层出不穷。

不甘示弱于 AZUR-1、CheckMate 8HW 或其他令人惊叹的 IO 突破,Chalabi 发布了 NICHE-2 的长期随访结果。

一言以蔽之?完美。

111 例局部晚期 dMMR 结肠癌患者。仅接受 6 周新辅助纳武利尤单抗/伊匹单抗治疗后行手术。

零复发。5 年总生存率 100%。

请记住,这些并非全是低风险肿瘤。许多属于高风险 III 期疾病。

我们仅用几周免疫治疗就治愈了患者。

现在,能否完全避免手术?

治疗胃肠癌的时代真好。

@TheGutOncLab @OncoAlert @Onco_Nexus

https://www.sciencedirect.com/science/article/pii/S0140673626016028

3098 浏览 · 57 赞 · 22 转发 · 3 回复

会议摘要
4736O按 Proffered paper 1: Genitourinary tumour, renal and urothelial 对上

Results from a phase 3 trial of neoadjuvant (neoadj) chemotherapy alone vs in combination with nivolumab followed by postsurgical adjuvant nivolumab in patients (pts) with muscle-invasive bladder cancer (MIBC)

https://esmocongress.esmo.org
4757RO按 Rapid oral 1: Genitourinary tumours, renal and urothelial 对上

Final pathological and radiological outcomes and initial EFS from a blinded, exploratory phase 2 trial of nivolumab ± visugromab in MIBC (GDFather-NEO)

https://esmocongress.esmo.org
LBA54按 Proffered paper: Melanoma and other skin tumours 对上

Primary analysis of HBI-8000-303: A randomized phase 3 trial of nivolumab plus HBI-8000 or placebo in advanced melanoma

https://esmocongress.esmo.org
NCT04884282NCT04884282按 - **标题 / Title:** Efficacy of Tedopi Plus Docetaxel or Tedopi Plus Nivolumab as Second-line Therapy in Metastatic Non-small-cell Lung Cancer Progressing After First-line Chemo-immunotherapy (Combi-TED) 对上

- **标题 / Title:** Efficacy of Tedopi Plus Docetaxel or Tedopi Plus Nivolumab as Second-line Therapy in Metastatic Non-small-cell Lung Cancer Progressing After First-line Chemo-immunotherapy (Combi-TED)

https://esmocongress.esmo.org
帖内回复
  1. A.n.n.@fireflyann

    @GIMedOnc I saw Dr @MyriamChalabi slides in 2018.. in Dutch... but could see the word of crc was changing!!!

  2. Nicholas Hornstein@GIMedOnc

    @agrothey Don’t get me started on ATOMIC…

  3. Axel Grothey@agrothey

    @GIMedOnc And move over, ATOMIC!

来源:Nicholas Hornstein · x.com

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