Paclitaxel +\-tovecimig: COMPANION-002 ph2/3
➡️prev treated #BTC wo actionable alterations
➡️ORR 17.1 v5.3%; DCR 62 v 37%
➡️mPFS 4.7 v 2.6mths - benefits seen at PFS2 noting crossover
➡️OS not sig but nb crossover
@myESMO #ESMO26 @OncoAlert
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FOLFIRI plus ramucirumab versus paclitaxel plus ramucirumab as second-line therapy for taxane-pretreated patients with advanced or metastatic gastroesophageal adenocarcinoma–Final results of the phase III IKFs602/AIO RAMIRIS Study
https://esmocongress.esmo.orgDESTINY-Breast11: MRI-assessed objective responses during neoadjuvant treatment (NAT) with trastuzumab deruxtecan (T-DXd) followed by paclitaxel + trastuzumab + pertuzumab (THP) vs dose-dense doxorubicin + cyclophosphamide followed by THP (
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https://esmocongress.esmo.org来源：Grainne O'Kane · x.com