Yakup Ergün· @dr_yakupergun · X·· 2 天前评分90
正文 · 机器翻译
#ESMO26 | HORIZON-Breast06
显著的 PFS 获益✨️
在 HER2-low mBC 中，trastuzumab rezetecan 相比化疗显著改善了 PFS：
16.4 vs 6.8 mo
获益在 HR+（HR 0.24）和 HR−（0.34）患者中保持一致
OS 数据仍不成熟，但已显现出令人鼓舞的趋势（HR 0.67）。
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会议摘要
LBA13按 Proffered paper 1: Breast cancer, early and advanced stage 对上
Trastuzumab rezetecan (SHR-A1811) in HER2-low advanced breast cancer (BC): A randomized, phase 3 study (HORIZON-Breast06)
https://esmocongress.esmo.org#ESMO26 | HORIZON-Breast06 HER2-low mBC after ≥1 prior line of chemo for metastatic disease, or in the first-line chemo setting after prior ET (if HR+). Trastuzumab rezetecan vs. physician’s choice of chemo PFS: 16.4 vs 6.8 mo (HR 0.27) ORR: 75.5% vs 41.2% Grade ≥3 TRAEs: 84.1% vs 67.9% ILD: 2.5%.在 X 查看被引用的帖子
来源：Yakup Ergün · x.com