The Lancet· Reena H Doshi, Irene Lubega, Pierre Muhoza, Grace Carlock, Arthur Brian Sekiziyivu, Alexandra Tuttle, Marjorie Najjengo, John Kayiwa, Rebecca Casey, Eric C Mossel, Winfred Nakato, Conrad Tumwine, Ellon Twinomuhwezi, Julius Lutwama, Annet Nankya, Leonara Rebecca Nabatanzi, Semakula Charles, Allison M Brown, Jennifer Harris, Leora Feldstein, Susan Chu, Hongjiang Gao, Andrew Kambugu, J Erin Staples, Terri B Hyde·· 20 天前精选评分52
乌干达9-23月龄儿童中17DD黄热病疫苗五分之一和半剂量与全剂量免疫原性比较：一项4期单盲随机临床试验
[Articles] Immunogenicity of fractional one-fifth and one-half doses of 17DD yellow fever vaccine compared with full dose in children aged 9–23 months in Uganda: a phase 4, single-blind, randomised clinical trial
导读
17DD黄热病疫苗的五分之一和半剂量在诱导初始血清转换方面均不劣于全剂量。结果支持在供应短缺期间对幼儿使用分剂量黄热病疫苗进行疫情应对。
来源：The Lancet · thelancet.com