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Yakup Ergün· @dr_yakupergun · X·· 23 小时前评分70

VOLGA

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#ESMO26 | VOLGA
新辅助 EV + 围手术期 durvalumab 在 MIBC 中展现出令人印象深刻的结果✅

一个重要细节:约 25% 的患者并非不符合顺铂治疗条件,而是拒绝接受顺铂治疗。

因此,该方案的潜在适用范围可能超越不符合顺铂治疗条件的患者

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会议摘要
LBA2按 Presidential Symposium I 对上

Perioperative durvalumab with or without tremelimumab plus neoadjuvant enfortumab vedotin in muscle-invasive bladder cancer: Results from the phase 3 VOLGA trial

https://esmocongress.esmo.org
引用@
#ESMO26 | VOLGA | Presidential Symposium-1 In cisplatin-ineligible/refusing MIBC, neoadjuvant EV + perioperative durvalumab significantly improved EFS and OS vs the control arm. EFS: HR 0.55 (24-month: 78% vs 69%) OS: HR 0.58 (24-month: 83% vs 75%) pCR: 45% vs 10% Impressive results! Unlike KEYNOTE-905/EV-303, EV was administered only in the neoadjuvant setting, with no adjuvant EV. I’m looking forward to the discussion during the session.
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来源:Yakup Ergün · x.com

CBACBA Frontier Insights (CFI)美国华人生物医药科技协会(CBA)www.cba-usa.org