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Zymeworks Inc.· @ZymeworksInc · X·· 2026-04-21评分60
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#AACR26:今天,生物偶联科学家兼组负责人Vincent Fung将在上午9:00至……之间介绍“ZW418的开发:一种双价PTK7靶向抗体-药物偶联物,采用新型泛RAS抑制剂载荷,用于治疗非小细胞肺癌”

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会议摘要
1686按 代号 ZW418 对上
Development of ZW418, a biparatopic PTK7-targeting antibody-drug conjugate incorporating a novel pan-RAS inhibitor payload for the treatment of non-small cell lung cancer

Luying Yang, Alex Wu, Vincent Fung, Kaylee J. Wu, Sara Weeres, Katina Mak, Taixiang Wang, Victoria Harman-McKenna, Allysha Bissessur, Jesse Leblanc, Vidhi Khanna, Matthew Bonderud, Jodi Wong, Rehan Higgins, Linglan Fu, Dunja Urosev, Raffaele Colombo, Graham A. Garnett, Jamie R. Rich, Stuart D. Barnscher

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来源:Zymeworks Inc. · x.com

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