Our team recently attended the @AACR Annual Meeting in San Diego! Thanks to Tongfei Wu and Heleen Roose for sharing preclinical data on o...

AACR 2026 现场信号· @ · X·2026-04-22 04:08· 2026-04-22评分60

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Our team recently attended the @AACR Annual Meeting in San Diego! Thanks to Tongfei Wu and Heleen Roose for sharing preclinical data on our oral PD-L1 small molecule inhibitors, ALG-093940 and ALG-094295 in a poster presentation. #AACR26 https://t.co/4JFOGVA6mb

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会议摘要

2818按代号 ALG-094295 对上

Preclinical Characterization of ALG-094295, a highly potent and orally bioavailable small molecule PD-1/PD-L1 inhibitor targeting dimerization, internalization and degradation of PD-L1

Heleen Roose, Kristina Rekstyte-Matiene, Sarah Stevens, Kusum Gupta, Sandra Chang, Nour Fayyad, Cheng Liu, Vladimir Serebryany, Lillian Adame, Kha Le, Antitsa Stoycheva, Dinah Misner, Lawrence M. Blatt, Sushmita Chanda, David B. Smith, Julian A. Symons, Andreas Jekle, Tongfei Wu

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2819按代号 ALG-093940 对上

Preclinical characterization of ALG-093940, a potent and orally bioavailable small molecule PD-1/PD-L1 inhibitor targeting PD-L1 dimerization, internalization and degradation

Heleen Roose, Kristina Rekstyte-Matien, Sarah Stevens, Kusum Gupta, Sandra Chang, Nour Fayyad, Cheng Liu, Vladimir Serebryany, Lillian Adame, Kha Le, Antitsa Stoycheva, Dinah Misner, Lawrence M. Blatt, Leonid Beigelman, Sushmita Chanda, David B. Smith, Julian A. Symons, Andreas Jekle, Tongfei Wu

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来源：AACR 2026 现场信号 · x.com