#ESMO26 DASL-HiCAP（ANZUP1801）主席论坛报告 @niazi_Dr7 @urotoday
⚡️MFS-CI 主要终点：HR 0.42，95%CI 0.27-0.66
⚡️所有次要终点均支持加用 Daro
⚡️加用 Daro 带来的额外毒性有限
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Darolutamide with androgen deprivation therapy (ADT) and definitive or salvage locoregional radiation therapy (RT) for localised, very high-risk prostate cancer: Interim analysis of an international, placebo-controlled, randomised phase 3 t
https://esmocongress.esmo.orgINTerpath-001: Phase 3 study of the mRNA-based individualized neoantigen therapy (INT) intismeran autogene (intismeran) plus pembrolizumab (pembro) vs pembro alone for adjuvant treatment of resected stage IIB-IV melanoma (MEL)
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https://esmocongress.esmo.org⚡️LBA4⚡️ DASL-HiCaP (ANZUP1801) Ph 3 RCT #ESMO26 Daro + ADT and definitive/salvage locoregional RT for very HR PCa @urotoday 🚨n=1,106; mFU 3.8 yrs; 85% definitive RT 🚨Primary EP MFS by CI: ⏫ for Daro vs PBO - 4-year MFS-CI 95% vs 88% - HR 0.42 (95% CI 0.27 to 0.66)在 X 查看被引用的帖子
来源：Zach Klaassen · x.com