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Nieves Martinez Lago MD PhD· @DraMartinezLago · X·· 16 小时前评分70

paclitaxel

正文 · 机器翻译

#ESMO26 🧬 COMPANION-002 | III期

👥 既往接受过治疗的 BTC
💊 紫杉醇 + tovecimig vs 紫杉醇

🎯 ORR:18% vs 5.3%
📈 mPFS:4.7 vs 2.6 个月
⏳ mOS:8.9 vs 9.4 个月

❌ 尽管 ORR 和 PFS 有所改善,但未带来 OS 获益。

💡 活性令人鼓舞,但尚非新的 SoC

@OncoAlert

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会议摘要
2878RO按 Rapid oral 1: Gastrointestinal tumour, upper digestive 对上

FOLFIRI plus ramucirumab versus paclitaxel plus ramucirumab as second-line therapy for taxane-pretreated patients with advanced or metastatic gastroesophageal adenocarcinoma–Final results of the phase III IKFs602/AIO RAMIRIS Study

https://esmocongress.esmo.org
543RO按 Rapid oral: Breast cancer, early stage 对上

DESTINY-Breast11: MRI-assessed objective responses during neoadjuvant treatment (NAT) with trastuzumab deruxtecan (T-DXd) followed by paclitaxel + trastuzumab + pertuzumab (THP) vs dose-dense doxorubicin + cyclophosphamide followed by THP (

https://esmocongress.esmo.org
LBA37按 Proffered paper: Gynaecological cancers 对上

Durvalumab (D) plus carboplatin/paclitaxel (CP) followed by D with or without olaparib (O) in advanced/recurrent endometrial cancer (a/rEC): Interim overall survival (OS) and safety from the randomised phase 3 DUO-E/GOG-3041/ENGOT-EN10 stud

https://esmocongress.esmo.org

来源:Nieves Martinez Lago MD PhD · x.com

CBACBA Frontier Insights (CFI)美国华人生物医药科技协会(CBA)www.cba-usa.org