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Nieves Martinez Lago MD PhD· @DraMartinezLago · X·· 19 小时前评分70

MET

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#ESMO26 🧬 Epsametostat (HH2853) | Phase II

🎯 Advanced epithelioid sarcoma
💊 Dual EZH1/2 inhibitor

👥 94 pts | 75 efficacy-evaluable

📈 ORR: 40% | DCR: 77.3%
⏳ mPFS: 13.1 mo | mDoR: 15.6 mo
🎯 mOS: Not reached

⚠️ G≥3 TRAEs: 39.4%

🚀 Primary endpoint met!

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会议摘要
1017P按 Developmental therapeutics 对上

Phase 1 first-in-human (FIH) results of YL211, a c-Met targeting antibody-drug conjugate (ADC), in patients (pts) with advanced solid tumors

https://esmocongress.esmo.org
NCT06110663NCT06110663按 - **标题 / Title:** A Study of HS-10241 Combined With Almonertinib Versus Platinum-based Chemotherapy in Treatment of Advanced NSCLC With MET Amplification After Failure of EGFR-TKI Therapy 对上

- **标题 / Title:** A Study of HS-10241 Combined With Almonertinib Versus Platinum-based Chemotherapy in Treatment of Advanced NSCLC With MET Amplification After Failure of EGFR-TKI Therapy

https://esmocongress.esmo.org

来源:Nieves Martinez Lago MD PhD · x.com

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