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Sara Tolaney· @stolaney1 · X·· 2 天前评分90

HER2

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NSABP B-42:
n=3966
median f/u 15.9 yrs
57% node-neg, 78% HER2-
39% prior tamoxifen
15 yr BCFI: HR 0.78
Distant Recurrence: HR 0.72
N-: HR0.78, N+ HR 0.69
OS HR 0.92

@OncoAlert #ESMO26

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会议摘要
1766RO按 Rapid oral 1: Breast cancer, advanced stage 对上

Health-related quality of life from HER2CLIMB-05: A phase 3 study of tucatinib versus placebo in combination with trastuzumab and pertuzumab as 1L maintenance therapy for HER2+ mBC

https://esmocongress.esmo.org
1780P按 HER2+ breast cancer 对上

Safety, social costs and quality of life (QOL) in HER2-positive (HER2+) breast cancer (BC) patients (pts) treated with pertuzumab + trastuzumab fixed-dose combination subcutaneous (PT FDC SC): The PERTURB study

https://esmocongress.esmo.org
1795TIP按 HER2+ breast cancer 对上

A global, interventional, open-label trial of trastuzumab deruxtecan (T-DXd)–based therapy in first-line HER2-positive metastatic breast cancer: DESTINY-Breast Guide

https://esmocongress.esmo.org
1842O按 Proffered paper 2: Breast cancer, early and advanced stage 对上

Efficacy and safety of atirmociclib (ATI) + fulvestrant (FUL) in patients (pts) with HR+/HER2– advanced/metastatic breast cancer (mBC) who progressed on prior CDK4/6 inhibitor (CDK4/6i) in a randomized phase 2 study (FOURLIGHT-1)

https://esmocongress.esmo.org
1844P按 HR+ breast cancer 对上

Gene-expression profiling of HR+/HER2- breast cancers arising in germline BRCA1/2 mutation carriers

https://esmocongress.esmo.org

来源:Sara Tolaney · x.com

CBACBA Frontier Insights (CFI)美国华人生物医药科技协会(CBA)www.cba-usa.org