@lungoncdoc is raising the question lung oncologists need before Madrid: if resistance lives in the TOP1 payload, a new antibody target may not rescue response, and most of the lun

MeDucation· @MeDucationai · X·2026-10-22 00:49· 4 天前评分45

正文 · 原文

@lungoncdoc is raising the question lung oncologists need before Madrid: if resistance lives in the TOP1 payload, a new antibody target may not rescue response, and most of the lung ADCs in play carry TOP1 payloads. #ESMO26 #LCSM

39 浏览 · 0 赞 · 0 转发 · 0 回复

引用@

Important implications for lung cancer, too. We’re behind breast cancer in understanding optimal ADC sequencing, but emerging data raise an important concern: switching targets may not overcome resistance when the payload remains the same... #ESMO26

在 X 查看被引用的帖子

来源：MeDucation · x.com