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Zach Klaassen· @zklaassen_md · X·· 1 天前评分70

DASL-HICAP

正文 · 机器翻译

⚡️LBA4⚡️ DASL-HiCaP (ANZUP1801) III 期 RCT #ESMO26

Daro + ADT 及根治性/挽救性局部区域放疗用于极高危前列腺癌 @urotoday

🚨n=1,106; 中位随访 3.8 年; 85% 根治性放疗
🚨主要终点 MFS(按 CI 判定):Daro 优于安慰剂 ⏫
- 4 年 MFS-CI 95% 对 88%
- HR 0.42 (95% CI 0.27 至 0.66)

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会议摘要
LBA4按 Presidential Symposium I 对上

Darolutamide with androgen deprivation therapy (ADT) and definitive or salvage locoregional radiation therapy (RT) for localised, very high-risk prostate cancer: Interim analysis of an international, placebo-controlled, randomised phase 3 t

https://esmocongress.esmo.org
LBA1按 Presidential Symposium I 对上

INTerpath-001: Phase 3 study of the mRNA-based individualized neoantigen therapy (INT) intismeran autogene (intismeran) plus pembrolizumab (pembro) vs pembro alone for adjuvant treatment of resected stage IIB-IV melanoma (MEL)

https://esmocongress.esmo.org
LBA2按 Presidential Symposium I 对上

Perioperative durvalumab with or without tremelimumab plus neoadjuvant enfortumab vedotin in muscle-invasive bladder cancer: Results from the phase 3 VOLGA trial

https://esmocongress.esmo.org
LBA3按 Presidential Symposium I 对上

Tarlatamab plus durvalumab (durva) vs durva as 1L maintenance (1LM) therapy following durva, platinum, and etoposide (1L durva + EP) in extensive-stage small cell lung cancer (ES-SCLC): Primary analysis of the phase 3 DeLLphi-305 trial

https://esmocongress.esmo.org

来源:Zach Klaassen · x.com

CBACBA Frontier Insights (CFI)美国华人生物医药科技协会(CBA)www.cba-usa.org