Distinguishing Clonal Hematopoiesis from Tumor HRR Alterations in Liquid Biopsy: Implications for PARP Inhibitor Use in #mCRPC. Presented by @EAntonarakis @UMNCancer, #ESMO26 writt

UroToday.com· @urotoday · X·2026-10-24 04:00· 1 天前评分45

正文 · 机器翻译

在液体活检中区分克隆性造血与肿瘤 HRR 突变：对 #mCRPC 中 PARP 抑制剂使用的启示。由 @EAntonarakis @UMNCancer 在 #ESMO26 上演示，@zklaassen_md 撰写报道 > https://bit.ly/4soadIo #ProstateCancer #PrecisionOncology @myESMO

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会议摘要

2218RONCT04746300按 Rapid oral: Genitourinary tumours, prostate, penile and testis 对上

Distinguishing clonal hematopoiesis (CH) from tumor homologous recombination repair (HRR) alterations in liquid biopsy: Implications for PARP inhibitor (PARPi) use in metastatic castration-resistant prostate cancer (mCRPC)

https://esmocongress.esmo.org

2220RONCT04746300按 Rapid oral: Genitourinary tumours, prostate, penile and testis 对上

Plasma ctDNA as standalone or adjunct to tumour tissue for HRR and PI3K/AKT genotyping in mCRPC: PROMPT (NCT04746300)

https://esmocongress.esmo.org

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