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Nieves Martinez Lago MD PhD· @DraMartinezLago · X·· 2 天前评分90

MET

正文 · 机器翻译

#ESMO26 💊 RAMIRIS | II/III 期

👥 317 例紫杉烷预治疗 GEA
🔀 FOLFIRI+Ram 对比 Pac+Ram

❌ 共同主要终点未达标
⏳ OS:8.7 对 7.5 个月(HR 0.95)
🎯 ORR:25.3% 对 22.6%
✅ PFS:5.5 对 3.7 个月(HR 0.70;p=.003)
⚠️ G≥3 不良事件:70% 对 68%

💡 PFS 获益但 OS 未改善

@OncoAlert

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会议摘要
1017P按 Developmental therapeutics 对上

Phase 1 first-in-human (FIH) results of YL211, a c-Met targeting antibody-drug conjugate (ADC), in patients (pts) with advanced solid tumors

https://esmocongress.esmo.org
NCT06110663NCT06110663按 - **标题 / Title:** A Study of HS-10241 Combined With Almonertinib Versus Platinum-based Chemotherapy in Treatment of Advanced NSCLC With MET Amplification After Failure of EGFR-TKI Therapy 对上

- **标题 / Title:** A Study of HS-10241 Combined With Almonertinib Versus Platinum-based Chemotherapy in Treatment of Advanced NSCLC With MET Amplification After Failure of EGFR-TKI Therapy

https://esmocongress.esmo.org

来源:Nieves Martinez Lago MD PhD · x.com

CBACBA Frontier Insights (CFI)美国华人生物医药科技协会(CBA)www.cba-usa.org