At #AACR26, Pepper Schedin, PhD (@OHSUKnight) spotlights early-onset breast cancer, with a focus on postpartum cases.

She explores emerging risk factors and what they mean for prevention and outcomes in young women.

Key takeaways:
•ER+ young on-set breast cancer is increasing.
•~75% of YOBC lethality occurs in ER+ cases, with highest mortality in PPBC.
•PPBC patients with classically good prognostic cancers are at risk for liver metastasis.
•Weaning-induced liver involution is the likely mechanism.
•Postpartum biology represents a unique opportunity to develop effective early detection/treatment strategies for YOBC.

#MoffittAACR26