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Erika Hamilton, MD, FASCO· @ErikaHamilton9 · X·· 1 天前评分70

ipatasertib

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#FINER fulvestrant +/- ipatasertib (AKTi)

45% of pts were pathway altered

PFS lengthened in ITT HR 0.68

and AKT altered cohorts HR 0.55

93% diarrhea, pretty high G2/3 rates

#ESMO26 #ESMOAmbassadors

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会议摘要
LBA14按 Proffered paper 2: Breast cancer, early and advanced stage 对上

A double-blind placebo controlled randomized phase III trial of fulvestrant and ipatasertib as treatment for HER-2 negative and estrogen receptor positive (ER+) metastatic breast cancer (MBC): Overall survival results of the CCTG/BCT MA.40/

https://esmocongress.esmo.org

来源:Erika Hamilton, MD, FASCO · x.com

CBACBA Frontier Insights (CFI)美国华人生物医药科技协会(CBA)www.cba-usa.org