Cell· Yuda Chen, Klaus Yserentant, Kibeom Hong, Kehan Chen, Yiming Kuang, Robert S. Picardo, Arghya Bhowmick, Arthur Charles-Orszag, Samuel J. Lord, Lei Lu, Kaipeng Hou, Samuel I. Mann, Sagar Bhattacharya, Maggie Horst, Jonathan B. Grimm, Luke D. Lavis, R. Dyche Mullins, William F. DeGrado, Bo Huang·· 2026-09-01评分47
De novo pan-rhodamine binders for fluorescence microscopy from mammalian cells to extremophiles
De novo pan-rhodamine binders for fluorescence microscopy from mammalian cells to extremophiles
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研究人员通过AI从头设计出名为Rhobins的通用罗丹明结合剂，具备高亮度、可逆结合和极高稳定性。Rhobins在活细胞/固定细胞、超分辨和单分子成像中性能超越现有标签，并能在75°C下实现对极端微生物的成像。
来源：Cell · cell.com