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Nieves Martinez Lago MD PhD· @DraMartinezLago · X·· 2 天前评分70

KRAS

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#ESMO26 💉 AMPLIFY-7P | Phase II

👥 144 pts | Resected PDAC
💊 Camupepimut (KRAS vaccine) vs observation

❌ Primary DFS endpoint not met:
23.8 vs 21.2 mo (HR 0.85; p=0.53)

🔬 Exploratory findings:
🧬 ctDNA+ predicts poor DFS (HR 6.56)
📈 No prior RT: DFS 23.8 vs 10.4 mo

💡 Signals warrant further investigation.

@OncoAlert

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会议摘要
2683P按 NSCLC, metastatic 对上

First-line (1L) olomorasib + pembrolizumab in KRAS G12C-mutant NSCLC: Updated results from LOXO-RAS-20001 and SUNRAY-01

https://esmocongress.esmo.org

来源:Nieves Martinez Lago MD PhD · x.com

CBACBA Frontier Insights (CFI)美国华人生物医药科技协会(CBA)www.cba-usa.org