Science· Swagata Goswami, Qiming Zhang, Abdullah Burak Yildiz, Upasana Das Adhikari, Akhouri Kishore Raghawan, Manon Bulliard, Sabhyata Sedhain, Odai Darawshi, Cigdem Elif Celik, Feyza Cansiz, Constantin P. Krempe, Jonas Rösler, Gabriele Allies, Sven W. Meckelmann, Chiashin Chi, Felix-Levin Hormann, Sven Heiles, Joseph Sedlak, Wesley Grace, George Eng, Ethan Reich, Chiara Alquati, Kevin J. Williams, Benjamin J. Read, Edrees H. Rashan, Zhixin Li, Anup Jnawali, Jose A. Ortiz, Chesta Jain, Charles A. Whittaker, Osman H. Yilmaz, Vikram Deshpande, Oliver J. Schmitz, Albert Sickmann, Autumn G. York, Douglas S. Kwon, Ulf Neumann, Maria Fedorova, Matthew G. Vander Heiden, Besim Ogretmen, Nilay S. Sethi, Alpaslan Tasdogan, Ömer H. Yilmaz·· 8 天前精选评分61
神经酰胺合成通过 YAP 驱动的再生程序介导结直肠癌转移
Ceramide synthesis mediates colorectal cancer metastasis through a YAP-driven regenerative program
导读
研究发现神经酰胺合成驱动结直肠癌转移，其机制涉及 YAP 信号通路激活的再生程序。该研究发表于 Science 期刊。
推荐理由
研究揭示了鞘脂代谢物神经酰胺在结直肠癌转移中的新机制，为靶向肿瘤微环境提供了潜在方向。
来源：Science · science.org