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Petros Grivas· @PGrivasMDPhD · X·· 16 小时前评分70

#PROSTATECANCER

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Exciting phase 3 trials data in metastatic #ProstateCancer @myESMO #ESMO26 #ESMOAmbassadors #PEACE1 #Capitello281 @Silke_Gillessen @neerajaiims @OncoAlert @OncBrothers @PCFnews @shilpaonc @EAntonarakis @Parminder1699 @Uromigos @montypal @docjavip @drenriquegrande @cdanicas

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会议摘要
1209RONCT04746300按 Rapid oral: Genitourinary tumours, prostate, penile and testis 对上

Neoadjuvant toripalimab combined with chemotherapy for locally advanced penile squamous cell carcinoma: A multicenter prospective, single-arm, phase II clinical trial

https://esmocongress.esmo.org
1210RONCT04746300按 Rapid oral: Genitourinary tumours, prostate, penile and testis 对上

Safety and efficacy of ixotatug vedotin (TORL-1-23), a claudin 6-targeted ADC, as monotherapy in germ cell tumors (GCT)

https://esmocongress.esmo.org
2217RONCT04746300按 Rapid oral: Genitourinary tumours, prostate, penile and testis 对上

Updated results from the phase 1b/2 KEYNOTE-365 cohort I: Pembrolizumab (pembro) + carboplatin and etoposide chemotherapy (chemo) or chemo alone for neuroendocrine prostate cancer (NEPC)

https://esmocongress.esmo.org
2218RONCT04746300按 Rapid oral: Genitourinary tumours, prostate, penile and testis 对上

Distinguishing clonal hematopoiesis (CH) from tumor homologous recombination repair (HRR) alterations in liquid biopsy: Implications for PARP inhibitor (PARPi) use in metastatic castration-resistant prostate cancer (mCRPC)

https://esmocongress.esmo.org
2219RONCT04746300按 Rapid oral: Genitourinary tumours, prostate, penile and testis 对上

Utility of ctDNA tumor fraction (TF) as a prognostic biomarker in TALAPRO-3: phase 3 study of talazoparib (TALA) + enzalutamide (ENZA) vs placebo (PBO) + ENZA in patients (pts) with homologous recombination repair (HRR) gene–mutated metasta

https://esmocongress.esmo.org
2220RONCT04746300按 Rapid oral: Genitourinary tumours, prostate, penile and testis 对上

Plasma ctDNA as standalone or adjunct to tumour tissue for HRR and PI3K/AKT genotyping in mCRPC: PROMPT (NCT04746300)

https://esmocongress.esmo.org
引用@
#ESMO26: Adding capivasertib to abiraterone and adding abiraterone to standard care resulted in significant improvements in #ProstateCancer in the phase III CAPItello-281 and PEACE-1 #ClinicalTrials, as discussed by Elena Castro 🔗 https://ow.ly/k8xU50ZZk08 #InsightsbyESMO
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来源:Petros Grivas · x.com

CBACBA Frontier Insights (CFI)美国华人生物医药科技协会(CBA)www.cba-usa.org