The Lancet· Michael D Jenkinson, Anna Rosala-Hallas, Felix Sahm, Nicolaus Andratschke, Keyoumars Ashkan, Damiano Balestrini, Helen Bulbeck, Sílvia Comas, Giovanna Culeddu, Kumar Das, Laura Fariselli, Karen Fowkerer, Priya Francis, Efstathia Gkioni, Vassilis Golfinopoulos, Thierry Gorlia, Neda Haghighi, Brian J Haylock, Dyfrig A Hughes, Mohsen Javadpour, Philippe Martinive, Helen M O Mayles, Perry Moore, Emilie Le Rhun, Nicola Rosenfelder, Gail Ryan, Michael Weller, Carrol Gamble, Matthias Preusser, Damien C Weber, ROAM/1308 Study Collaborators·· 7 天前精选评分55
放疗对比观察在WHO 2级非典型脑膜瘤完全切除后的三期随机试验结果（ROAM/EORTC-1308）
[Articles] Radiotherapy versus observation following surgical resection of WHO grade 2 atypical meningioma (ROAM/EORTC-1308): an international, multicentre, open-label, phase 3, randomised controlled trial
导读
ROAM/EORTC-1308三期随机试验显示，WHO 2级非典型脑膜瘤完全切除后辅助放疗可降低复发风险。研究者建议当预防复发优先于放疗潜在迟发副作用时考虑该方案，决策需基于个体化医患讨论。
推荐理由
这项三期试验为WHO 2级非典型脑膜瘤术后辅助放疗提供了随机对照证据，帮助临床权衡复发风险与放疗副作用。
来源：The Lancet · thelancet.com