Pat LoRusso (@YaleCancer) presenting new phase 1 data for ZW191, a FRa TOPO1i ADC!

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AACR 2026 现场信号· @ · X·2026-04-22 07:24· 2026-04-22评分60

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Pat LoRusso (@YaleCancer) 正在公布 ZW191 的最新 I 期数据。这是一款 FRa TOPO1i ADC！

#AACR26 https://t.co/aeSpyDD4ok

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会议摘要

CT306NCT06555744按代号 ZW191 对上

Phase 1 first-in-human multicenter open-label study of ZW191, a folate receptor α (FRα)-targeting antibody-drug conjugate (ADC), in patients with advanced solid tumors: Part 1 dose-escalation results

Patricia LoRusso, David Sommerhalder, Kosei Hasegawa, Kenichi Harano, David S. Tan, Noboru Yamamoto, David M. O’Malley, Kathleen N. Moore, Sarah E. Church, Lin Lu, Sabeen Mekan, Pranshul Chauha, Jung-Yun Lee

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来源：AACR 2026 现场信号 · x.com