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Nurullah İlhan,MD· @drnurullahilhan · X·· 17 小时前评分70

FOURLIGHT-1

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FOURLIGHT-1:接受CDK4/6i治疗后的HR+/HER2−乳腺癌。

Atirmociclib + fulvestrant达到了II期PFS终点:
9.4个月 vs 6.6个月;HR 0.60。

对照组:fulvestrant或everolimus/exemestane。
未显示相较后者的单独优效性。

#FOURLIGHT1 #ESMO2026 #BCSM

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会议摘要
1842O按 Proffered paper 2: Breast cancer, early and advanced stage 对上

Efficacy and safety of atirmociclib (ATI) + fulvestrant (FUL) in patients (pts) with HR+/HER2– advanced/metastatic breast cancer (mBC) who progressed on prior CDK4/6 inhibitor (CDK4/6i) in a randomized phase 2 study (FOURLIGHT-1)

https://esmocongress.esmo.org

来源:Nurullah İlhan,MD · x.com

CBACBA Frontier Insights (CFI)美国华人生物医药科技协会(CBA)www.cba-usa.org