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OncoAlert· @OncoAlert · X·· 15 小时前评分70

SAFFRON

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The #OncoAlertTOPTweet Day 3 #ESMO26
Post by NEJM

SAFFRON
In EGFR-mutated, MET-positive NSCLC progressing on osimertinib, adding savolitinib significantly improves progression-free and overall survival compared with platinum–pemetrexed, with similar rates of severe adverse events.

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引用@
Presented at #ESMO26: In patients with 𝘌𝘎𝘍𝘙-mutated and MET-altered non–small-cell lung cancer that had progressed during osimertinib therapy, osimertinib plus savolitinib (a MET tyrosine kinase inhibitor) led to longer survival than platinum–pemetrexed. Full phase 3 SAFFRON trial results: https://nej.md/4hXdueb @myESMO
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