MASTERPLAN

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The open-label, phase 2, multicentre MASTERPLAN randomised trial by the Australasian Gastro-Intestinal Trials Group (AGITG) showed that perioperative chemotherapy plus SBRT significantly reduced locoregional recurrence in high-risk, localised PDAC. Compared with perioperative chemotherapy alone, adding SBRT did not significantly increase toxicity; the authors say the strategy warrants investigation in larger studies.

Excerpted from thelancet.com

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Oct 24

18:59
x.com
#ESMO26 Day 1 highlight for me: MASTERPLAN, now in Lancet Oncology.
06:00
x.com
📣#NewPublication: Results from the #MASTERPLAN randomised phase 2 trial have been presented at #ESMO26 and published in @TheLancetOncol.
05:41
x.com
Nice to see the MASTERPLAN study presented #ESMO26 and published in @TheLancetOncol !
00:32
x.com
Big result from @_ShankarSiva and the MASTERPLAN team. The detail for fellows: this is a randomized phase 2 whose primary endpoint was 12-month locoregional recurrence, so the surv
00:00
thelancet.com
[Articles] Perioperative chemotherapy and stereotactic body radiotherapy versus perioperative chemotherapy alone in patients with high-risk, localised pancreatic cancer (MASTERPLAN): an open-label, phase 2, multicentre, randomised trial of the Australasian Gastro-Intestinal Trials Group
The open-label, phase 2, multicentre MASTERPLAN randomised trial by the Australasian Gastro-Intestinal Trials Group (AGITG) showed that perioperative chemotherapy plus SBRT significantly reduced locoregional recurrence in high-risk, localised PDAC. Compared with perioperative chemotherapy alone, adding SBRT did not significantly increase toxicity; the authors say the strategy warrants investigation in larger studies.

Oct 23

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Heat now 39·Peak in the comparable set 77 (Oct 24 07:00)·Change over 24h in the comparable set -41%·Participants now 11

Participants counted11

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